SELANK
$29.99
In stock
- These products are intended for laboratory research purposes only, and are not for human or animal consumption. The products are not intended to diagnose, treat, cure, or prevent any disease. The products should not be used as a food, drug, cosmetic, or other household use.
Description
Selank is a synthetic heptapeptide analog of the endogenous immunopeptide tuftsin, studied for its non-sedating anxiolytic and nootropic profile. It allosterically modulates GABA-A receptors, upregulates BDNF, and inhibits enkephalin-degrading enzymes — without the tolerance, dependence, or cognitive impairment associated with classical anxiolytics.
Research Overview
Selank is a stabilized analog of tuftsin extended to a heptapeptide for improved CNS stability and activity. Its anxiolytic mechanism is distinct from benzodiazepines: rather than directly potentiating GABA-A inhibition, Selank allosterically modulates GABAergic tone while simultaneously optimizing serotonin and dopamine system activity.
Research documents its inhibition of enkephalin-degrading enzymes — extending endogenous opioid signaling — alongside BDNF upregulation that adds a nootropic dimension. Its cytokine-modulating properties, particularly regulation of IL-6, position it at the intersection of the nervous and immune systems.
Key Features
- Synthetic 7-amino acid peptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro); tuftsin analog
- Allosteric modulator of GABA-A receptors — anxiolytic without sedation or dependence
- Upregulates BDNF expression in the hippocampus
- Inhibits enkephalin-degrading enzymes, prolonging endogenous opioid activity
- Regulates IL-6 and cytokine balance via neuroimmune pathways
- Half-life: ~3 minutes (nasal); rapid CNS onset within 20 minutes
Common Research Uses
- Commonly studied for anxiety reduction without sedation, amnesia, or dependence
- Researched in relation to generalized anxiety, PTSD models, and social stress
- Investigated for cognitive enhancement and memory consolidation
- Studied for BDNF upregulation and neuroprotective properties
- Researched for immunomodulatory effects through cytokine regulation
Product Specifications
- Format: Lyophilized powder
- Vial size: 10mg
- Storage: Freeze at −20°C (lyophilized); refrigerate at 2–8°C after reconstitution; protect from light; use within 28 days
Disclaimer: For research purposes only. Not for human consumption.
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